Nonossifying Fibroma

http://www.learningradiology.com/notes/bonenotes/nonossifyingfibpage.htm

Nonossifying Fibroma

AKA: Nonosteogenic fibroma, fibroxanthoma, xanthogranuloma of bone

  • 30 to 40% children over two years have one or more lesions
  • Most common between 8-20 years of age
  • Usually occur in metaphysis of one (75%) or more (25%) of the tubular bones
  • Most often occur in lower extremities around knee
    • Fewer than 10% occur in upper extremities
  • Characteristics
    • Geographic
    • Lytic
    • Multilobulated
    • Metaphyseal
    • Usually intramedullary
    • Eccentric
    • Well-marginated
    • Sclerotic rim
    • Endosteal scalloping
  • Most lesions heal spontaneously by being replaced with normal bone
    • Migrate away from epiphysis
  • May undergo pathologic fracture or rarely cause rickets
    • Do not undergo malignant transformation

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